What is acetate gossypol?
Acetate gossypol is a natural product that has been shown to induce infertility in guinea pigs and humans. Gossypol binds to the Bcl-xL and Bcl-2 proteins and has a Kis of 0.5-0.6 mM. In a study on gossypol, the drug produced significant reductions in pituitary cell size, degranulation, and hypertrophy. The rat pituitary cells exhibited […]