Rosemary, also known as Youancao, is a plant of the sage genus Lamiaceae. Rosemary is a versatile economic crop from which antioxidants, rosemary essential oil, etc. can be extracted.
Ursolic acid is a kind of triterpenoid compound that exists in natural plants. The high content of ursolic acid is shiny prismatic (absolute ethanol) or fine-hair-like needle-like crystals (dilute ethanol), and the low content is brown or yellow. Yellow-green powder with a special smell. It has a variety of biological effects such as sedation, anti-inflammatory, antibacterial, anti-diabetic, anti-ulcer, and lowering blood sugar. Ursolic acid also has obvious antioxidant function, so it is widely used as a raw material for medicine and cosmetics.
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Functions of Ursolic acid:
1. The clinical manifestations of ursolic acid can significantly and rapidly reduce alanine aminotransferase, serum aminotransferase, reduce jaundice, increase appetite, anti-fibrosis, and restore liver function.
2. Ursolic acid can obviously inhibit the proliferation of HL-60 cells and induce their apoptosis and has resistance to a variety of carcinogens and carcinogens.
3. Ursolic acid can inhibit 5-lipoxygenase and cyclooxygenase activities during the metabolism of arachidonic acid, and prevent the production of prostaglandins and leukotrienes, indicating that ursolic acid is a strong antioxidant.
4. Ursolic acid can respectively inhibit the production of superoxide induced by formyl methionyl-leucyl-phenylalanine (fMLP) and arachidonic acid and has antibacterial and antiviral effects.
5. Clinical trials have proved that ursolic acid and its malonic acid derivatives can inhibit HIV-1 protease.